Serotonin is a powerful
neurotransmitter that is synthesized from tryptophan, contained in
food. The lack of serotonin is associated with symptoms of depression, anxiety,
anguish and sadness. Foods rich in tryptophan, act as natural antidepressants, leading to increased
serotonin without psychoactive drugs.
Scientific studies have demonstrated that increased serotonin is associated with a feeling of well-being, relaxation, increased self esteem and concentration.
Scientific studies have demonstrated that increased serotonin is associated with a feeling of well-being, relaxation, increased self esteem and concentration.
Low levels of
serotonin are also associated with aggressive states, depression and anxiety
and even migraines, because when serotonin levels drop, blood vessels dilate.
Serotonergic function is essentially inhibitory. Influences on sleep and is also related to mood, emotion and depressive states. Affects vascular function as well as the frequency of the heartbeat, regulates the secretion of hormones such as growth. Changes in the level of this substance are associated with mental imbalances such as schizophrenia or autism. It also plays an important role in certain anxiety disorders.
Serotonergic function is essentially inhibitory. Influences on sleep and is also related to mood, emotion and depressive states. Affects vascular function as well as the frequency of the heartbeat, regulates the secretion of hormones such as growth. Changes in the level of this substance are associated with mental imbalances such as schizophrenia or autism. It also plays an important role in certain anxiety disorders.
Use of
melatonin in place of serotonin:
Melatonin produced in the pineal gland acts as an endocrine hormone since it is released into the bloodstream, while that produced in the retina and the gastrointestinal tract acts as a paracrine hormone. The site of action of melatonin are neural (hippocampus, pituitary, hypothalamus, retina, pineal gland and others) and non-neural (gonads, intestine, blood vessels, immune cells, and others).
Role of melatonin:
Melatonin receptors are specific, saturable and reversible, and neural sites of action affect circadian rhythms. The non-neural affect reproductive function and peripherals have different functions.
Melatonin influences the immune system aging, cardiovascular disease, changes in daily rhythm, sleep, psychiatric conditions. Although their mismanagement or abuse can lead to generalized information.
Most animals have cycles of fertility and infertility. There are players of long days and short days. The former are activated by the increased length of photoperiod, and the latter by the decrease. The pinealectomy blocks the effects of light on gonadal function. The administration of melatonin reproduce the phenomenon in pinealectomized animals. Short-day players have their maximum activity in winter. Then neither melatonin nor antigonadal progonadal, but is a sign chronological and reports circulating in the body when found (calendar information), is a neuroendocrine-player interaction.
Melatonin is not therefore a drug or natural remedy created by man, but of an endogenous substance, a hormone produced by an endocrine gland, called pineal gland or epiphyses.
This gland, which develops embryonically from the roof of the diencephalon (part of the forebrain of vertebrates), has always played an important role associated with vision in the evolutionary history of vertebrates. In fact, it is believed that the ancestors of the vertebrates was the epiphysis medial eye, third eye, which complemented the bilateral eyes. Among living vertebrates, only some exceptional cases such as lampreys and some reptiles have a medial dorsal eye, which is usually very small. In these animals this organ works primarily to detect changes in light levels. In birds and, above all, in mammals, the pineal gland is a glandular organ entirely. However, although the pineal not an eye in most vertebrates, what is certain is that receives visual information indirectly through other diencephalic region, called suprachiasmatic nuclei. The hormone melatonin is synthesized in the pinealocytes (pineal gland cells) from and only from serotonin by two steps controlled by as many enzymes. The synthesis and release of melatonin shows a marked circadian rhythm, leading to the peak of secretion at night (although there are few examples of increased secretion during the day). This circadian rhythm of melatonin production in the body provides valuable information on the time of day and time of year and as a result, the hormonal cycle to other circadian rhythms as well as other seasonal cycles of reproduction
Melatonin produced in the pineal gland acts as an endocrine hormone since it is released into the bloodstream, while that produced in the retina and the gastrointestinal tract acts as a paracrine hormone. The site of action of melatonin are neural (hippocampus, pituitary, hypothalamus, retina, pineal gland and others) and non-neural (gonads, intestine, blood vessels, immune cells, and others).
Role of melatonin:
Melatonin receptors are specific, saturable and reversible, and neural sites of action affect circadian rhythms. The non-neural affect reproductive function and peripherals have different functions.
Melatonin influences the immune system aging, cardiovascular disease, changes in daily rhythm, sleep, psychiatric conditions. Although their mismanagement or abuse can lead to generalized information.
Most animals have cycles of fertility and infertility. There are players of long days and short days. The former are activated by the increased length of photoperiod, and the latter by the decrease. The pinealectomy blocks the effects of light on gonadal function. The administration of melatonin reproduce the phenomenon in pinealectomized animals. Short-day players have their maximum activity in winter. Then neither melatonin nor antigonadal progonadal, but is a sign chronological and reports circulating in the body when found (calendar information), is a neuroendocrine-player interaction.
Melatonin is not therefore a drug or natural remedy created by man, but of an endogenous substance, a hormone produced by an endocrine gland, called pineal gland or epiphyses.
This gland, which develops embryonically from the roof of the diencephalon (part of the forebrain of vertebrates), has always played an important role associated with vision in the evolutionary history of vertebrates. In fact, it is believed that the ancestors of the vertebrates was the epiphysis medial eye, third eye, which complemented the bilateral eyes. Among living vertebrates, only some exceptional cases such as lampreys and some reptiles have a medial dorsal eye, which is usually very small. In these animals this organ works primarily to detect changes in light levels. In birds and, above all, in mammals, the pineal gland is a glandular organ entirely. However, although the pineal not an eye in most vertebrates, what is certain is that receives visual information indirectly through other diencephalic region, called suprachiasmatic nuclei. The hormone melatonin is synthesized in the pinealocytes (pineal gland cells) from and only from serotonin by two steps controlled by as many enzymes. The synthesis and release of melatonin shows a marked circadian rhythm, leading to the peak of secretion at night (although there are few examples of increased secretion during the day). This circadian rhythm of melatonin production in the body provides valuable information on the time of day and time of year and as a result, the hormonal cycle to other circadian rhythms as well as other seasonal cycles of reproduction
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